Public Health Messages to Address Vaccine Hesitancy

Sponsor
University of Manitoba (Other)
Overall Status
Completed
CT.gov ID
NCT03395106
Collaborator
Canadian Immunization Research Network (Other)
883
1
4
4
218.5

Study Details

Study Description

Brief Summary

Views on vaccines range from those who are strongly supportive to those who are stridently opposed and will not budge from identity-based core beliefs about vaccines. In between these poles are numerous others who can delay, be reluctant (but still accept), or refuse/accept some vaccines for their children but not others. It is for these vaccine-hesitant parents that constitute the 'middle ground' of this spectrum where the most immediate and productive gains can be made towards enhancing vaccination acceptance and improving uptake. However, navigating this noisy communications environment is difficult, given the array of confusing and conflicting information available from multiple and competing sources. To date, there is no consensus on how best to use communication to respond to vaccine hesitancy. Building on two Canada-wide surveys of parents, the goal of this research is to identify which communication strategies show the greatest impact in reducing parental vaccine hesitancy and improving vaccination intentions.

The specific objectives are to:
  1. Develop and pre-test four variations of news media stories that vary by source (parent versus physician) and content (intuitive versus deliberative);

  2. Examine the impact of vaccine hesitant parents' exposure to vaccine communications that vary in source (parent versus physician) and content (intuitive versus deliberative) on primary (vaccine hesitant attitudes) and secondary (vaccine intentions) outcomes; and

  3. Explore which media story variation may be more effective in improving vaccination attitudes and intentions for different parental decision-making styles (deliberative versus intuitive).

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Parent source
  • Behavioral: Doctor source
  • Behavioral: Deliberative content
  • Behavioral: Intuitive content
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
883 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Factorial design 2x2Factorial design 2x2
Masking:
Single (Outcomes Assessor)
Masking Description:
Statisticians completing the analysis of the primary outcome will be blinded.
Primary Purpose:
Health Services Research
Official Title:
Developing and Evaluating Public Health Messages to Address Vaccine Hesitancy
Actual Study Start Date :
Jul 9, 2018
Actual Primary Completion Date :
Nov 9, 2018
Actual Study Completion Date :
Nov 9, 2018

Arms and Interventions

Arm Intervention/Treatment
Experimental: Parent source + intuitive story content

Behavioral: Parent source
Having a parent feature prominently in a news story

Behavioral: Intuitive content
News story content focuses on the consequences of not vaccinating (including vaccine preventable diseases) and the decisional regret.

Experimental: Doctor source + intuitive story content

Behavioral: Doctor source
Having a doctor feature prominently in a news story

Behavioral: Intuitive content
News story content focuses on the consequences of not vaccinating (including vaccine preventable diseases) and the decisional regret.

Experimental: Parent source + deliberative content

Behavioral: Parent source
Having a parent feature prominently in a news story

Behavioral: Deliberative content
News story content includes process of weighing the risks/benefits of vaccinating, the importance of vaccines for community protection, and concludes with a recommendation to vaccinate.

Experimental: Doctor source + deliberative content

Behavioral: Doctor source
Having a doctor feature prominently in a news story

Behavioral: Deliberative content
News story content includes process of weighing the risks/benefits of vaccinating, the importance of vaccines for community protection, and concludes with a recommendation to vaccinate.

Outcome Measures

Primary Outcome Measures

  1. Vaccine Hesitancy [Change in baseline measured up to 1 day after content delivery]

    Parent Attitudes about Childhood Vaccines (PACV). The PACV is a validated 15 question survey on vaccine hesitancy.

Secondary Outcome Measures

  1. Intention to Vaccinate [Change in baseline measured up to 1 day after content delivery]

    intention to vaccinate item using a 5 point likert scale ranging from very unlikely to vaccinate to very likely to vaccinate, and see if there is a one-response shift in participant intentions among vaccine hesitant parents.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Parents over 18 living in Canada with a YOUNGEST child is less than 24 months.
Exclusion Criteria:
  • Parents who have a YOUNGEST child older than 24 months

  • A parent who is pregnant, before the first trimester is complete

Contacts and Locations

Locations

Site City State Country Postal Code
1 University of Manitoba Winnipeg Manitoba Canada R2M 3Y9

Sponsors and Collaborators

  • University of Manitoba
  • Canadian Immunization Research Network

Investigators

  • Principal Investigator: Michelle Driedger, PhD, University of Manitoba

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
University of Manitoba
ClinicalTrials.gov Identifier:
NCT03395106
Other Study ID Numbers:
  • H2016:390
First Posted:
Jan 10, 2018
Last Update Posted:
Oct 10, 2019
Last Verified:
Oct 1, 2019
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by University of Manitoba

Study Results

No Results Posted as of Oct 10, 2019