The Validation of Rockall Scoring System in Predicting Outcomes From Variceal Bleeding

Sponsor
National Center for Gastroentestinal and Liver Disease (Other)
Overall Status
Completed
CT.gov ID
NCT06147115
Collaborator
(none)
150
3.3

Study Details

Study Description

Brief Summary

Objective This study aims to evaluate the validation of the Rockall scoring system in predicting the outcomes of variceal bleeding among Sudanese patients.

Design/Method A cross-sectional hospital-based study involved 150 adult Sudanese patients presenting with upper gastrointestinal bleeding (UGIB) of variceal origin. Patients with UGIB resulting from causes other than varices and those who declined participation were excluded. Data were collected through a structured questionnaire complemented by upper gastrointestinal tract endoscopy findings, and patients were followed up until discharge.

Results The study encompassed 150 patients, predominantly male (117, 78%), aged between 18 and 60 years (n=119, 79%), residing mainly in central regions (134, 89%). The leading presenting complaints included hematemesis (70, 46.7%) and melena (22, 14.6%). Notably, peri-portal fibrosis (101, 67.3%) and cirrhosis (24, 16%) were the primary etiological factors, with a significant prevalence of alcohol consumption (87, 58%). Concerning the grade of esophageal varices, grades III and IV were most prevalent (67, 44.7% and 47, 31.3%, respectively), and fundal varices were identified in 13 patients (8.7%). The mean Rockall score was 3.83 ± 1.99, indicating moderate severity. Additionally, the Rockall score showed significant associations with the number of sessions, complications, bleeding recurrence, duration of hospital stay, and mortality (p < 0.05).

Conclusion Understanding the significance of the Rockall scoring system and its applicability to Sudanese patients with variceal bleeding has the potential to guide more effective strategies in the management of upper gastrointestinal tract bleeding, ultimately improving patient outcomes and reducing morbidity and mortality.

Condition or Disease Intervention/Treatment Phase
  • Other: Assessment tool to determine severity of GI bleeding

Study Design

Study Type:
Observational
Actual Enrollment :
150 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
The Validation of Rockall Scoring System in Predicting Outcomes From Variceal Bleeding in Sudanese Patients: Cross-sectional Study.
Actual Study Start Date :
Jun 1, 2012
Actual Primary Completion Date :
Sep 1, 2012
Actual Study Completion Date :
Sep 10, 2012

Outcome Measures

Primary Outcome Measures

  1. the validation of the Rockall scoring system in predicting the outcomes of variceal bleeding among Sudanese patients [June 2012 - Sep 2012]

    The primary outcome measure in this study appears to be the validation of the Rockall scoring system in predicting the outcomes of variceal bleeding among Sudanese patients presenting to the Mohammed Salih Idris Bleeding Center (MSIBC). The study aims to assess the effectiveness of the Rockall scoring system in predicting mortality, bleeding recurrence, and other clinical outcomes in Sudanese patients with variceal bleeding. The Rockall scoring system incorporates various factors, including age, evidence of shock, coexisting medical conditions, and the presence of visible signs of hemorrhage. The study investigates the association between Rockall scores and clinical outcomes such as mortality, bleeding recurrence, complications, duration of hospital stay, and interventions conducted. The validation of the Rockall scoring system in the context of variceal bleeding in Sudan is crucial for risk stratification and guiding the management of patients with variceal bleeding.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • aged 18 years and older

  • primary complaints of upper GI bleeding

Exclusion Criteria:
  • Patients with upper GI bleeding resulting from causes other than varices

  • who declined to participate in the study

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • National Center for Gastroentestinal and Liver Disease

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
National Center for Gastroentestinal and Liver Disease
ClinicalTrials.gov Identifier:
NCT06147115
Other Study ID Numbers:
  • GastroentestinalLiverRockall
First Posted:
Nov 27, 2023
Last Update Posted:
Nov 27, 2023
Last Verified:
Nov 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 27, 2023