Value of PCT When Diagnosing Candidemia

• Sponsor: Karolinska University Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT05385107
• Collaborator: (none)
• Enrollment: 49
• Location: 1
• Actual Duration (Months): 140.4
• Patients Per Site Per Month: 0.3

Study Details

Study Description

Brief Summary

This study is a retrospective analysis to identify and compare the shift in inflammatory biomarkers in ICU patients immediately before and after the first identification of candidemia.

Condition or Disease	Intervention/Treatment	Phase
The Value of Procalcitonin in Patients With Suspected Candidemia	Diagnostic Test: Serum procalcitonin concentration

Detailed Description

As above.

Study Design

• Study Type: Observational
• Actual Enrollment: 49 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Official Title: Value of PCT When Diagnosing Candidemia
• Actual Study Start Date: Apr 1, 2010
• Actual Primary Completion Date: Dec 31, 2015
• Actual Study Completion Date: Dec 12, 2021

Outcome Measures

Primary Outcome Measures

1. Absolute procalcitonin concentration [9 days]

2. Shift (trend) procalcitonin concentration [9 days]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria (all has to be fullfilled):

• ICU patients with blood cultures showing growth of Candida species

• clinical records including daily data on WBC, CRP, Procalcitonin and body temperature

Exclusion Criteria:

• Age lower than 18 years

• blood cultures with growth of Candida species before ICU admission

• incomplete records of daily WBC, CRP, Procalcitonin or body temperature

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Karolinska University Hospital Solna	Stockholm		Sweden	17176

Sponsors and Collaborators

• Karolinska University Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Johan Petersson, Associate Profesor, Senior Consultant, Karolinska University Hospital
• ClinicalTrials.gov Identifier: NCT05385107
• Other Study ID Numbers: EPN 2017/806-31 (Candida-PCT)
• First Posted: May 23, 2022
• Last Update Posted: May 23, 2022
• Last Verified: May 1, 2022

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Candidemia

Study Results

No Results Posted as of May 23, 2022