Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard.
Sponsor
KU Leuven (Other)
Overall Status
Completed
CT.gov ID
NCT05070000
Collaborator
(none)
304
40.9
Study Details
Study Description
Brief Summary
This study is a retrospective evaluation of all patients treated surgically for appendicitis over a period of 3 years at the Sint- Andries Hospital, Tielt. Belgium. The goal is to evaluate the value of ultrasound (US), computed tomography (CT) and laboratory testing in diagnosing acute appendicitis and to look for the possible impact on the treatment.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
304 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard - Retrospective Cohort Study.
Actual Study Start Date
:
Jan 1, 2016
Actual Primary Completion Date
:
Dec 31, 2018
Actual Study Completion Date
:
May 31, 2019
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| US Ultrasound |
|
| CT Computed tomography |
|
| US after CT Ultrasound after Computed tomography |
Diagnostic Test: Radiologic examination
Patients underwent US, CT or CT after US
|
Outcome Measures
Primary Outcome Measures
- Sensitivity and specificity of diagnostic test [3 years]
For US and CT sensitivity and specificity for diagnosing acute appendicitis were evaluated.
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- suspicion of acute appendicitis
Exclusion Criteria:
- none
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- KU Leuven
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Drake FT, Flum DR. Improvement in the diagnosis of appendicitis. Adv Surg. 2013;47:299-328. Review.
- Drake FT, Mottey NE, Farrokhi ET, Florence MG, Johnson MG, Mock C, Steele SR, Thirlby RC, Flum DR. Time to appendectomy and risk of perforation in acute appendicitis. JAMA Surg. 2014 Aug;149(8):837-44. doi: 10.1001/jamasurg.2014.77.
- Marzuillo P, Germani C, Krauss BS, Barbi E. Appendicitis in children less than five years old: A challenge for the general practitioner. World J Clin Pediatr. 2015 May 8;4(2):19-24. doi: 10.5409/wjcp.v4.i2.19. eCollection 2015 May 8. Review.
- Shogilev DJ, Duus N, Odom SR, Shapiro NI. Diagnosing appendicitis: evidence-based review of the diagnostic approach in 2014. West J Emerg Med. 2014 Nov;15(7):859-71. doi: 10.5811/westjem.2014.9.21568. Epub 2014 Oct 7. Review.
Responsible Party:
Louis Haentjens,
M.D,
KU Leuven
ClinicalTrials.gov Identifier:
NCT05070000
Other Study ID Numbers:
- Appendixstudy
First Posted:
Oct 6, 2021
Last Update Posted:
Oct 6, 2021
Last Verified:
Oct 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Louis Haentjens,
M.D,
KU Leuven
Additional relevant MeSH terms: