Improving Venous Thromboembolism Prophylaxis

Sponsor
Mayo Clinic (Other)
Overall Status
Completed
CT.gov ID
NCT01304108
Collaborator
(none)
3,000
1
3
15.9
188.3

Study Details

Study Description

Brief Summary

Preventing the formation of blood clots in the veins so they do not injure leg veins or travel to the lungs, also called venous thromboembolism prophylaxis (VTE-P) is an essential component of safe in-patient care, yet it is deployed sub-optimally in many hospitals, including The investigators own. Two prior VTE-P improvement projects were completed at Mayo Clinic hospitals, one in the Department of Medicine, and the other in selected divisions of the Department of Surgery. Both projects resulted in marked improvement in the percentage of patients receiving appropriate VTE-P. This project seeks to utilize the lessons learned from these two pilots along with known best practices for "spreading" to deploy methods that enhance VTE-P to the entire hospitalized population. The investigators seek appropriate VTE-P rates exceeding 95%.

Condition or Disease Intervention/Treatment Phase
  • Other: VTE-P Tollgate
  • Other: BLAZE Pop up
  • Other: Usual Care
Phase 4

Detailed Description

Venous thromboembolism prophylaxis (VTE-P) is an essential component of safe in-patient care, yet it is deployed sub-optimally in many hospitals, including our own. Two prior VTE-P improvement projects were completed at Mayo Clinic hospitals, one in the Department of Medicine, and the other in selected divisions of the Department of Surgery. Both projects resulted in marked improvement in the percentage of patients receiving appropriate VTE-P. This project seeks to utilize the lessons learned from these two pilots along with known best practices for "spreading" to deploy methods that enhance VTE-P to the entire hospitalized population. The investigators seek appropriate VTE-P rates exceeding 95%. This began as a quality improvement project. The investigators have taken baseline measures of VTE-P rates in our hospitals, intervened with various electronic prompts to use appropriate VTE-P, and have and will re-measure VTE-P rates. The investigators intend to present and publish our methods and results so that lessons learned may be shared and applied elsewhere.

Study Design

Study Type:
Interventional
Actual Enrollment :
3000 participants
Allocation:
Non-Randomized
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Health Services Research
Official Title:
Spreading and Improving DVT Prophylaxis at Mayo Clinic (DVT-P-Spread)
Study Start Date :
Jan 1, 2009
Actual Primary Completion Date :
May 1, 2010
Actual Study Completion Date :
May 1, 2010

Arms and Interventions

Arm Intervention/Treatment
Experimental: Order Set

Insertion of VTE-P Order Set "tollgate" in all active admission and transfer orders.

Other: VTE-P Tollgate
Add VTE-P tollgate order set that requires a decision regarding VTE-P for every patient admitted or transferred in our hospital system

Experimental: Clinical Decision Support Pop-up

Deploy rules-based pop-up that reminds ordering clinicians when patients do not have an active VTE-P plan.

Other: BLAZE Pop up
Develop and deploy a rules-based popup that reminds prescribers interfacing with the orders system when a patient does not have an active VTE-P plan.

Active Comparator: Usual Care

Usual care, without the experimental additions

Other: Usual Care
No addition to the baseline system for care

Outcome Measures

Primary Outcome Measures

  1. % of in patients with an appropriate VTE prophylaxis plan [Baseline to 1 month]

    The investigators will measure the number of patients in a statistically valid random sample of hospitalized patients who have a VTE-prophylaxis plan consistent with current recommendations.

Secondary Outcome Measures

  1. Clinically significant complications of VTE-P anticoagulant therapy [baseline to 1 month]

    The investigators will determine the rate of bleeding complications in inpatients using a statistically valid random sample of hospitalized patients. The investigators will also determine the rate of procedure delays due to VTE-P related anticoagulation.

Eligibility Criteria

Criteria

Ages Eligible for Study:
17 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Inpatients with age > 17 years old
Exclusion Criteria:
  • Outpatients

  • Inpatients with age less than or equal to 17 years old

Contacts and Locations

Locations

Site City State Country Postal Code
1 Mayo Clinic in Rochester Rochester Minnesota United States 55905

Sponsors and Collaborators

  • Mayo Clinic

Investigators

  • Principal Investigator: Timothy Morgenthaler, MD, Mayo Clinic

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
, ,
ClinicalTrials.gov Identifier:
NCT01304108
Other Study ID Numbers:
  • 09-006359
First Posted:
Feb 25, 2011
Last Update Posted:
Feb 25, 2011
Last Verified:
Feb 1, 2011

Study Results

No Results Posted as of Feb 25, 2011