Is There a Correlation Between the Pulmonary Artery Pressure and the Acceleration of the Flow in the Pulmonary Artery Evaluated by Transesophageal Echocardiography (TOE) ?

Sponsor
Assistance Publique Hopitaux De Marseille (Other)
Overall Status
Unknown status
CT.gov ID
NCT01947257
Collaborator
(none)
50
1
1
16
3.1

Study Details

Study Description

Brief Summary

The measure of the pulmonary artery pressure (PAP) is a very useful index in intensive care to estimate right ventricular after load. The reference technique for this measure is the right catheterism which is an invasive technique. It is possible to estimate the pulmonary artery pressure by using transthoracic echocardiography (TTE) which allows, using the continuous Doppler, the measure of maximum speed of tricuspid regurgitation (TRvmax). The measure of the TRvmax can however be difficult for intensive care patients with little echogenicity or impossible for those having no tricuspid leak. The evaluation of the tricuspid regurgitation is also particularly difficult using TOE. To avoid these drawbacks, one can use the analysis of the pulmonary ejection in the pulmonary artery (PAAT) with TOE. However, the data of the literature are controversial on this method and it was not validated in mechanically ventilated intensive care patients.

The aim of this work is to compare three methods of measure of the PAP: the measure TRVMAX (by means of the tricuspid leak) by transthoracic echocardiography, the measure of the TAAP by transesophageal ultrasound and the direct measure of the pulmonary pressures by right catheterization, in ventilated patients already monitored with a catheter in the right cavities for usual indications in intensive care (ARDS, shock). We shall analyze then the correlation between the TRVmax, the TAAP and the pressures measured by the right catheterism which serves as reference technique.

Condition or Disease Intervention/Treatment Phase
  • Other: the measure TRVMAX
  • Other: the measure of the pulmonary artery
  • Other: the direct measure of the pulmonary pressures
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
50 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Is There a Correlation Between the Pulmonary Artery Pressure and the Acceleration of the Flow in the Pulmonary Artery Evaluated by Transesophageal Echocardiography (TOE) ?
Study Start Date :
Sep 1, 2013
Actual Primary Completion Date :
Jul 1, 2014
Anticipated Study Completion Date :
Jan 1, 2015

Arms and Interventions

Arm Intervention/Treatment
Other: ventilated patients

Other: the measure TRVMAX
by transthoracic echocardiography

Other: the measure of the pulmonary artery
by transesophageal ultrasound

Other: the direct measure of the pulmonary pressures
by right catheterization

Outcome Measures

Primary Outcome Measures

  1. measure of the pulmonary artery pressure [12 months]

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Patients aged over 18 years

  • Admitted to intensive care

  • Mechanically ventilated and sedated

  • Carrying a right catheterization

  • Making a ETO indicated by the medical team or doctor in charge of the patient

Exclusion Criteria:
  • Patients under 18 years

  • expectant mother

  • Patients without health insurance

  • Refusal to close

Contacts and Locations

Locations

Site City State Country Postal Code
1 Assistance Publique Hopitaux de Marseille Marseille France 13354

Sponsors and Collaborators

  • Assistance Publique Hopitaux De Marseille

Investigators

  • Study Director: LOIC MONDOLONI, Assistance Publique Hopitaux De Marseille

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Assistance Publique Hopitaux De Marseille
ClinicalTrials.gov Identifier:
NCT01947257
Other Study ID Numbers:
  • 2013-A00730-45
  • 2013-19
First Posted:
Sep 20, 2013
Last Update Posted:
Sep 1, 2014
Last Verified:
Aug 1, 2014

Study Results

No Results Posted as of Sep 1, 2014