Comparison of Therapeutic Efficacy Between Intralesional Bleomycin and Cryotherapy in Plantar Warts

• Sponsor: Combined Military Hospital Abbottabad (Other)
• Overall Status: Completed
• CT.gov ID: NCT05752435
• Collaborator: (none)
• Enrollment: 102
• Location: 1
• Arms: 2
• Actual Duration (Months): 6
• Patients Per Site Per Month: 17

Study Details

Study Description

Brief Summary

A randomized control trial to compare the efficacy difference between intralesional bleomycin and cryotherapy in treating plantar warts.

Condition or Disease	Intervention/Treatment	Phase
Viral Wart	Procedure: COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS	N/A

Detailed Description

In spite of many available studies on bleomycin and cryotherapy in treating warts, little head-to-head research is carried out to compare the efficacy of these treatments. This study shows clear difference in the clearance of warts treated with intralesional bleomycin and cryotherapy.

Study Design

• Study Type: Interventional
• Actual Enrollment: 102 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Intervention Model Description: Randomized Control Trial (RCT)Randomized Control Trial (RCT)
• Masking: Single (Outcomes Assessor)
• Masking Description: cure
• Primary Purpose: Treatment
• Official Title: Comparison of Therapeutic Efficacy Between Intralesional Bleomycin and Cryotherapy in Plantar Warts
• Actual Study Start Date: Jul 1, 2022
• Actual Primary Completion Date: Dec 31, 2022
• Actual Study Completion Date: Dec 31, 2022

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: BLEOMYCIN COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS	Procedure: COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS; comparison of therapeutic efficacy between intralesional bleomycin and cryotherapy in plantar warts
Active Comparator: CRYOTHERAPY COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS	Procedure: COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS; comparison of therapeutic efficacy between intralesional bleomycin and cryotherapy in plantar warts

Outcome Measures

Primary Outcome Measures

1. comparative effecacy of intra lesional bleomycin vs cryotherapy in treating plantar warts within 30 days of treatment [30 days of treatment]

   Intralesional bleomycin is more effective than cryotherapy in treating plantar warts within

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 50 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria

-healthy individuals of both genders between 18 to 50 years

Exclusion Criteria

• Pregnant and Lactating women

• history of vascular diseases/ chilblains

• Immunocompromised patients

• Treated previously for warts

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Adeel Siddiqui	ABbottabad	KPK	Pakistan

Sponsors and Collaborators

• Combined Military Hospital Abbottabad

Investigators

• Study Director: Adeel Dr Siddiqui, FCPS, cmh abbottabad

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Muhammad Adeel Siddiqui, Head of Department of Dermatology, Combined Military Hospital Abbottabad
• ClinicalTrials.gov Identifier: NCT05752435
• Other Study ID Numbers: CMHAbbottabad-Derma
• First Posted: Mar 2, 2023
• Last Update Posted: Mar 2, 2023
• Last Verified: Feb 1, 2023

• Individual Participant Data (IPD) Sharing Statement: Yes
• Plan to Share IPD: Yes
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Warts; Bleomycin

Study Results

No Results Posted as of Mar 2, 2023