Evaluation of Visual Parameters by Visual Evoked Potentials Captured by EEG

Sponsor
Université Catholique de Louvain (Other)
Overall Status
Recruiting
CT.gov ID
NCT05675852
Collaborator
(none)
100
1
4
25.2

Study Details

Study Description

Brief Summary

This project will be based on an approach that has already proven itself in the field of the development of low-level visual functions such as visual acuity, vernier acuity and contrast sensitivity (Norcia & Tyler, 1985): scanning visual evoked potentials" (sVEP), a special case of steady-state visual evoked potentials (SSVEP). While SSVEPs consist of presenting a visual stimulus periodically, sVEPs are SSVEPs where the value of a parameter (e.g. the contrast of the stimulus) varies. This variation ("scanning") makes it possible to determine the threshold value where an electroencephalographic (EEG) response is perceived, and thus to evaluate visual parameters such as visual acuity, vernier acuity and contrast sensitivity. In this study we therefore record the amplitude of the EEG electrical signal during the presentation of low-level stimuli such as spatial frequency gratings or increasing or decreasing contrast.

Condition or Disease Intervention/Treatment Phase
  • Other: 68-electrode electroencephalography with steady state visual evoked potentials

Study Design

Study Type:
Observational
Anticipated Enrollment :
100 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Evaluation of Visual Parameters in Healthy and Visually Impaired Adults Using the Sweep and Oddball Technique Associated With Visual Evoked Potentials Captured by EEG
Actual Study Start Date :
Dec 1, 2022
Anticipated Primary Completion Date :
Jan 1, 2023
Anticipated Study Completion Date :
Apr 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Healthy participants

Healthy participants aged from 1 to 75 years old. All experiments conducted in this study will make use of the electroencephalogram (EEG) recording technique. Healthy participants cannot participate if they suffer from dermatosis on the scalp. There is no other contraindication to the practice of an EEG, which simply consists of recording the electrical activity of the brain on a trace, after application of a conductive gel on the scalp where sensors connected to a recording device are placed. We will collect the cerebral electrical response by the technique of steady state visual evoked potentials (SSVEP) which consists of presenting a visual stimulus periodically to interpret the EEG signal according to those variations.

Other: 68-electrode electroencephalography with steady state visual evoked potentials
Electroencephalography is registered through a 68-electrode electroencephalography while stimuli will be presented at the centre of the screen at a distance of 150cm. The pattern of visual stimulation is based on the technique of steady state visual evoked potentials. These potentials consist of the presentation of a visual stimulus at a (relatively fast) periodic rate to produce an EEG signal over the occipital cortex exactly at the frequency of stimulation. By varying the value of a parameter of the stimulation (e.g. the contrast of the stimulus) varies. This variation makes it possible to determine the threshold value where an EEG response is perceived, and thus to evaluate visual parameters such as visual acuity, contrast sensitivity or recognition of more complex shapes.

Outcome Measures

Primary Outcome Measures

  1. Threshold of visual recognition of low and high grade visual stimuli [4 months]

    Fast periodic visual stimulation using stimuli such as gratings, checkerboards, words and faces

Eligibility Criteria

Criteria

Ages Eligible for Study:
1 Year to 75 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Absence of ocular pathologies except for refractive errors

  • Absence of neurologic conditions

Exclusion Criteria:
  • Participants using neurologic or psychiatric drugs

  • Scalp pathology

Contacts and Locations

Locations

Site City State Country Postal Code
1 Institute Of NeuroSciences Woluwe-Saint-Lambert Bruxelles Belgium 1200

Sponsors and Collaborators

  • Université Catholique de Louvain

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Université Catholique de Louvain
ClinicalTrials.gov Identifier:
NCT05675852
Other Study ID Numbers:
  • 2017%244
First Posted:
Jan 9, 2023
Last Update Posted:
Jan 9, 2023
Last Verified:
Jan 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Jan 9, 2023