The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee

Sponsor

Meir Medical Center (Other)

Overall Status

Completed

CT.gov ID

NCT01297361

Collaborator

(none)

Enrollment

Location

Arm

Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Vitamin B12 deficiency is more widespread in the population than has been assumed so far. Since a deficiency in this vitamin can lead to irreversible neurological damage, early diagnosis is essential. Vitamin B12 is synthesized exclusively in micro-organisms, and in humans it is an essential component in methyl group transfer and cell division. The vitamin is crucially involved in the proliferation, maturation, and regeneration of neural cells. In combination with folic acid, as an enzymatic essential cofactor in the metabolism of homocysteine, vitamin B12 maintains low homocysteine levels. The aim of the present study is to investigate the relationship between religious origin and age, and Vitamin B12 and Folic acid plasma levels in non Jewish population in Western Galilee. The investigators assumption is that the results of the study will contribute to early detection and treatment of Vitamin B12 and Folic acid deficiencies in order to prevent long term complications.

Condition or Disease	Intervention/Treatment	Phase
Vitamin B12 Deficiency Folic Acid Deficiency	Other: Blood Sample	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

90 participants

Allocation:

Randomized

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Diagnostic

Study Start Date :

Feb 1, 2011

Actual Primary Completion Date :

Nov 1, 2011

Actual Study Completion Date :

Aug 1, 2012

Arms and Interventions

Arm	Intervention/Treatment
Other: Plasma Vitamin B12 and Folic acid levels Blood sample was drawn	Other: Blood Sample Blood sampling for diagnosis of vitamins deficiencies

Arm

Intervention/Treatment

Other: Plasma Vitamin B12 and Folic acid levels

Blood sample was drawn

Other: Blood Sample

Blood sampling for diagnosis of vitamins deficiencies

Outcome Measures

Primary Outcome Measures

The number of participants of each religious origin group with folic acid deficiency [10 months]
The association between religious origin (Christians,Muslims and Druze) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly.
The number of participants of each age group with Vitamin B12 deficiency [10 months]
The association between age groups (18-40, 41-65 and above 65 years old) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly
The number of participants of each age group with folic acid deficiency [10 months]
The association between age groups (18-40, 41-65 and above 65 years old) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly
The number of participants of each religious origin group with Vitamin B12 deficiency [10 months]
The association between religious origin (Cristians, Muslims and Druze) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of these vitamins will be treated accordingly.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Age:18 and older
Able to understand and to sign informed consent

Exclusion Criteria:

Gastrointistinal Diseases
Malignancy
Psychiatric disorders
Pregnancy
Treatment with Vit B12 or Folic acid

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Clalit health services	Kfar Yassif		Israel	24908

Sponsors and Collaborators

Meir Medical Center

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Meir Medical Center

ClinicalTrials.gov Identifier:

NCT01297361

Other Study ID Numbers:

K.Hassan

First Posted:

Feb 16, 2011

Last Update Posted:

Apr 23, 2013

Last Verified:

Mar 1, 2012

Additional relevant MeSH terms:

Vitamin B 12 Deficiency

Folic Acid Deficiency

Study Results

No Results Posted as of Apr 23, 2013