Vitamin D, HbA1c and Vitamin B12 Levels in Patients

Sponsor

Hacettepe University (Other)

Overall Status

Completed

CT.gov ID

NCT05745779

Collaborator

(none)

606

Enrollment

Location

Actual Duration (Months)

200.5

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Abstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification.

Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.

Result:

Conclusion:

Condition or Disease	Intervention/Treatment	Phase
Serum HbA1c and Vitamin D, Vitamin B12 Values in Periodontal Diseases	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Detailed Description

bstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification as determined by the American Academy of Periodontology and the European Federation of Periodontology (AAP-EFP) Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.

Study Design

Study Type:

Observational

Actual Enrollment :

606 participants

Observational Model:

Other

Time Perspective:

Retrospective

Official Title:

Serum Vitamin D, HbA1c and Vitamin B12 Levels in Patients With Gingivitis and Periodontitis Stages

Actual Study Start Date :

Aug 11, 2022

Actual Primary Completion Date :

Oct 11, 2022

Actual Study Completion Date :

Nov 11, 2022

Arms and Interventions

Arm	Intervention/Treatment
Gingivitis 0% interdental bone loss	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12 Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study.
Stage 1 periodontitis 0-15% interdental bone loss	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12 Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study.
Stage 2 Periodontitis 15-33% interdental bone loss	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12 Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study.
Stage 3 Periodontitis >33% interdental bone loss with potential for additional tooth loss	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12 Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study.
Stage 4 Periodontitis >%33 interdental bone loss with potantial for loss of dentition	Diagnostic Test: HbA1c, Vitamin D, Vitamin B12 Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study.

Outcome Measures

Primary Outcome Measures

HbA1c [t0:baseline]
serum Hemoglobin A1c value
Vitamin D [t0 : baseline]
serum Vitamin D value
Vitamin B12 [t0:baseline]
serum Vitamin B12 value

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 80 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

Patients diagnosed with gingivitis or periodontitis with complete periodontal diagnostic data (Gingival Index(Löe, 1967), Plaque Index(Löe, 1967), Periodontal pocket depths(PD), Clinical Attachment loss (CAL), Radiological data- Interdental Bone loss (IBL) data
Non-smoker
Vit D, HbA1c and B12 vit in blood on the date of application to the clinic and/or in the last 3 months. Patients with data on values were included in the study.