PEW: Wasting in Chronic Kidney Disease

• Sponsor: Hospices Civils de Lyon (Other)
• Overall Status: Completed
• CT.gov ID: NCT03135717
• Collaborator: (none)
• Enrollment: 48
• Actual Duration (Months): 6

Study Details

Study Description

Brief Summary

Protein energy wasting is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of dialysis. It covers 20 to 70% of patients diagnosed with chronic kidney disease according to the degree of evolution of the disease and the diagnostic method.

Mechanisms of PEW are based mainly on anorexia and metabolic abnormalities caused by kidney disease. Nutritional treatment differs depending on the stage of the kidney disease acute or chronic treated whether or not by dialysis. Nutritional monitoring should be regular, individualized and collaborative to detect a risk of PEW or treat installed PEW. Refeeding techniques should allow all the nutritional needs. Their indications depend on the clinic, biochemical assessment and nutrient intake.

Condition or Disease	Intervention/Treatment	Phase
Chronic Kidney Hospitalized	Dietary Supplement: Nutritional care

Study Design

• Study Type: Observational
• Actual Enrollment: 48 participants
• Observational Model: Cohort
• Time Perspective: Cross-Sectional
• Official Title: Wasting in Chronic Kidney Disease: Refeeding Techniques and Artificial Nutrition Practices
• Actual Study Start Date: Dec 1, 2011
• Actual Primary Completion Date: Jun 1, 2012
• Actual Study Completion Date: Jun 1, 2012

Outcome Measures

Primary Outcome Measures

1. Nutritional care evaluated with questionnaire [Since admissions to hospital, up to 4 weeks]

Secondary Outcome Measures

1. body composition [Since admissions to hospital, up to 4 weeks]

2. physical activity [Since admissions to hospital, up to 4 weeks]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 44 Years to 73 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Patients with kidney disease

• Patients hospitalized in a university hospital renal ward

Exclusion Criteria:

• Hospitalization less than two weeks

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Hospices Civils de Lyon

Investigators

• Principal Investigator: Denis Fouque, Pr, Hospices Civils de Lyon

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Hospices Civils de Lyon
• ClinicalTrials.gov Identifier: NCT03135717
• Other Study ID Numbers: 69HCL14-253
• First Posted: May 1, 2017
• Last Update Posted: May 1, 2017
• Last Verified: Apr 1, 2017

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Hospices Civils de Lyon: Chronic kidney disease; Enteral nutrition; Oral nutritional supplements; Parenteral nutrition; Refeeding; Wasting
• Additional relevant MeSH terms: Kidney Diseases; Renal Insufficiency, Chronic; Wasting Syndrome; Cachexia

Study Results

No Results Posted as of May 1, 2017