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CRISPRA-CAS9

Showing 1 - 25 of 456
STUDY
CONDITIONS
INTERVENTIONS
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Viral Keratitis, Blindness Eye, Herpes Simplex Virus Infection Trial in Shanghai (BD111 Adult single group Dose)

Completed
  • Viral Keratitis
  • +3 more
  • BD111 Adult single group Dose
  • Shanghai, Shanghai, China
    Eye & Ent Hospital of Fudan University
Aug 20, 2022

Gene Editing as a Therapeutic Approach for Rett Syndrome

Recruiting
  • Rett Syndrome
  • Gene editing in vitro
  • Siena, Italy
    University of Siena
Feb 13, 2023

Carbapenem-Resistant Enterobacteriaceae Infection Trial in Jinan (CAZ/AVI plus Aztreonam, Conventional treatment)

Recruiting
  • Carbapenem-Resistant Enterobacteriaceae Infection
  • CAZ/AVI plus Aztreonam
  • Conventional treatment
  • Jinan, Shandong, China
    Mingju Hao
Apr 29, 2023

Glioblastoma Trial in Milwaukee (Gallium maltolate (500 mg), Gallium maltolate (1,000 mg), Gallium maltolate (1,500 mg))

Recruiting
  • Glioblastoma
  • Gallium maltolate (500 mg)
  • +3 more
  • Milwaukee, Wisconsin
    Froedtert Hospital & the Medical College of Wisconsin
Sep 20, 2022

Beta-Thalassemia, Thalassemia, Hematologic Diseases Trial (CTX001)

Not yet recruiting
  • Beta-Thalassemia
  • +6 more
  • CTX001
  • (no location specified)
Jul 26, 2022

Transfusion Dependent Beta-Thalassaemia Trial in Guangzhou, Shenzhen, Tianjin (ET-01)

Active, not recruiting
  • Transfusion Dependent Beta-Thalassaemia
  • ET-01
  • Guangzhou, Guangdong, China
  • +3 more
May 9, 2022

Beta-Thalassemia, Thalassemia, Genetic Diseases, Inborn Trial in Worldwide (CTX001)

Active, not recruiting
  • Beta-Thalassemia
  • +4 more
  • CTX001
  • Stanford, California
  • +11 more
Nov 30, 2022

COVID-19 Respiratory Infection Trial (PD-1 and ACE2 Knockout T Cells)

Not yet recruiting
  • COVID-19 Respiratory Infection
  • PD-1 and ACE2 Knockout T Cells
  • (no location specified)
Aug 13, 2021

Clear Cell Renal Cell Carcinoma, Cervical Carcinoma, Esophageal Carcinoma Trial in Nashville (CTX131)

Recruiting
  • Clear Cell Renal Cell Carcinoma
  • +4 more
  • CTX131
  • Nashville, Tennessee
    Research Site 1
Mar 21, 2023

Prognosis of Ischemic Stroke Due to Large-artery Atherosclerosis

Recruiting
  • Ischemic Stroke
  • Large-Artery Atherosclerosis (Embolus/Thrombosis)
  • carotid artery stenting
  • +6 more
  • Wuhan, China
    Tongji Hospital, Tongji Medical College, Huazhong University of
Oct 31, 2022

Diabetes, Type 1 Trial in Warsaw (Phenofibrate, Placebo)

Recruiting
  • Diabetes Mellitus, Type 1
  • Warsaw, Mazowieckie, Poland
  • +1 more
Jun 8, 2023

Relapsed/Refractory Acute Myeloid Leukemia (AML) Trial in Dresden, Heidelberg (Donor-derived CD34+ HSC with CRISPR/Cas9-mediated

Not yet recruiting
  • Relapsed/Refractory Acute Myeloid Leukemia (AML)
  • Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion
  • Gemtuzumab Ozogamicin
  • Dresden, Germany
  • +1 more
Dec 20, 2022

B-cell Lymphoma, Non-Hodgkin Lymphoma, B-cell Malignancy Trial (CTX112)

Not yet recruiting
  • B-cell Lymphoma
  • +7 more
  • CTX112
  • (no location specified)
Dec 12, 2022

Liver Cancer, Lung Cancer, Breast Cancer Trial in Guangzhou (TILs and CAR-TILs targeting HER2, Mesothelin, PSCA, MUC1, Lewis-Y,

Recruiting
  • Liver Cancer
  • +7 more
  • TILs and CAR-TILs targeting HER2, Mesothelin, PSCA, MUC1, Lewis-Y, GPC3, AXL, EGFR, Claudin18.2/6, ROR1, GD1, or B7-H3
  • Guangzhou, China
    Second Affiliated Hospital of Guangzhou Medical University
Apr 9, 2021

NSCLC, Metastatic Non Small Cell Lung Cancer, Stage IV NSCLC Trial in Duarte, Minneapolis (Fludarabine, Cyclophosphamide, CISH

Not yet recruiting
  • Carcinoma, Non-Small-Cell Lung
  • +5 more
  • Duarte, California
  • +1 more
Dec 7, 2022

T Cell Lymphoma Trial in Australia, Canada, United States (CTX130)

Recruiting
  • T Cell Lymphoma
  • CTX130
  • Duarte, California
  • +9 more
May 16, 2022

Gastrointestinal Ulcer Haemorrhage, Bacterial Infection Due to Helicobacter Pylori (H. Pylori) Trial in United Kingdom

Active, not recruiting
  • Gastrointestinal Ulcer Haemorrhage
  • Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
  • Lansoprazole 30mg, Clarithromycin 500mg, Metronidazole 400mg
  • Placebo lansoprazole 30mg, clarithromycin 500mg, metronidazole 400mg
  • Belfast, United Kingdom
  • +5 more
Apr 27, 2021

Solid Tumor, Adult Trial in Beijing (anti-mesothelin CAR-T cells)

Unknown status
  • Solid Tumor, Adult
  • anti-mesothelin CAR-T cells
  • Beijing, China
    Biotherapeutic Department and Hematology Department of Chinese P
Aug 6, 2020

Multiple Myeloma Trial in Worldwide (CTX120)

Active, not recruiting
  • Multiple Myeloma
  • CTX120
  • Chicago, Illinois
  • +9 more
Jul 14, 2022

Appetitive Behavior Trial in Leeds (Unheated Whey Protein (UWP) beverage, Heated Whey Protein (HWP) beverage, Casein (Cas)

Recruiting
  • Appetitive Behavior
  • Unheated Whey Protein (UWP) beverage
  • +3 more
  • Leeds, West Yorkshire, United Kingdom
    University of Leeds
Apr 28, 2021

A Long-term Follow-up Study in Subjects Who Received CTX001

Enrolling by invitation
  • Beta-Thalassemia
  • +6 more
  • CTX001
  • New York, New York
  • +12 more
Nov 18, 2022

Beta-Thalassemia, Thalassemia, Genetic Diseases, Inborn Trial in Nashville (CTX001)

Recruiting
  • Beta-Thalassemia
  • +4 more
  • CTX001
  • Nashville, Tennessee
  • +5 more
Feb 2, 2023

Beta-Thalassemia Trial in China (BRL-101)

Recruiting
  • Beta-Thalassemia
  • Guangzhou, Guangdong, China
  • +3 more
Nov 7, 2022

Gastrointestinal Epithelial Cancer, Gastrointestinal Tumors, Cancer of Gastrointestinal Tract Trial in Minneapolis

Recruiting
  • Gastrointestinal Epithelial Cancer
  • +10 more
  • Minneapolis, Minnesota
    Masonic Cancer Center, University of Minnesota
Aug 20, 2021

Sickle Cell Disease, Hydroxyurea Failure, Hydroxyurea Intolerance Trial in Nashville (CTX001)

Recruiting
  • Sickle Cell Disease
  • +4 more
  • CTX001
  • Philadelphia, Pennsylvania
  • +3 more
Jan 24, 2023