GDC0449
Showing 1 - 25 of 42
Clear Cell Chondrosarcoma, Dedifferentiated Chondrosarcoma, Locally Advanced Chondrosarcoma Trial in France (Laboratory
Active, not recruiting
- Clear Cell Chondrosarcoma
- +6 more
- Laboratory Biomarker Analysis
- +2 more
-
Bordeaux, France
- +5 more
Sep 20, 2022
Chronic GVHD Trial in Ann Arbor, Salt Lake City (Laboratory Biomarker Analysis, Vismodegib)
Terminated
- Chronic Graft Versus Host Disease
- Laboratory Biomarker Analysis
- Vismodegib
-
Ann Arbor, Michigan
- +1 more
Jun 22, 2021
Basal Cell Nevus Syndrome, Gorlin Syndrome Trial in Oakland, New York (GDC-0449)
Completed
- Basal Cell Nevus Syndrome
- Gorlin Syndrome
-
Oakland, California
- +1 more
Dec 16, 2020
Keratocystic Odontogenic Tumor Trial in New York (vismodegib)
Completed
- Keratocystic Odontogenic Tumor
-
New York, New YorkNYU Bluestone Center For Cllinical Research
Feb 1, 2021
Basal Cell Nevus Syndrome, Gorlin's Syndrome Trial in Oakland, New York (Vismodegib, Aminolevulinic acid %20 topical solution)
Completed
- Basal Cell Nevus Syndrome
- Gorlin's Syndrome
- Vismodegib
- Aminolevulinic acid %20 topical solution
-
Oakland, California
- +2 more
Oct 8, 2020
Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma Trial in
Not yet recruiting
- Anatomic Stage III Breast Cancer AJCC v8
- +14 more
- Biopsy
- +25 more
-
Portland, OregonOHSU Knight Cancer Institute
Jul 12, 2022
Metastatic Pancreatic Cancer Trial in Scottsdale, Baltimore, Philadelphia (Gemcitabine, nab-Paclitaxel, GDC-0449)
Completed
- Metastatic Pancreatic Cancer
- Gemcitabine, nab-Paclitaxel, GDC-0449
-
Scottsdale, Arizona
- +2 more
Apr 2, 2019
Skin Basal Cell Carcinoma Trial in Palo Alto (Pembrolizumab, Vismodegib)
Completed
- Skin Basal Cell Carcinoma
- Pembrolizumab
- Vismodegib
-
Palo Alto, CaliforniaStanford University School of Medicine
Mar 6, 2019
Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7, Stage IIB Prostate Cancer AJCC v7 Trial in United States (Goserelin
Terminated
- Prostate Adenocarcinoma
- +2 more
- Goserelin Acetate
- +3 more
-
Ann Arbor, Michigan
- +4 more
Feb 6, 2019
Extensive Stage Small Cell Lung Carcinoma, Recurrent Small Cell Lung Carcinoma Trial in United States (drug, biological, other)
Completed
- Extensive Stage Small Cell Lung Carcinoma
- Recurrent Small Cell Lung Carcinoma
- Cisplatin
- +4 more
-
Scottsdale, Arizona
- +300 more
Dec 10, 2020
Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer Trial in
Completed
- Acinar Cell Adenocarcinoma of the Pancreas
- +4 more
- vismodegib
- +6 more
-
Scottsdale, Arizona
- +2 more
Apr 4, 2019
Recurrent Pancreatic Carcinoma, Stage IV Pancreatic Cancer Trial in Ann Arbor (Gemcitabine Hydrochloride, Laboratory Biomarker
Completed
- Recurrent Pancreatic Carcinoma
- Stage IV Pancreatic Cancer
- Gemcitabine Hydrochloride
- +2 more
-
Ann Arbor, MichiganUniversity of Michigan Comprehensive Cancer Center
Aug 2, 2017
Healthy Trial (GDC-0449 oral capsules (non-labeled), GDC-0449 IV injection (labeled), CDC-0449 oral suspension (labeled))
Completed
- Healthy
- GDC-0449 oral capsules (non-labeled)
- +2 more
- (no location specified)
Jun 23, 2017
Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma Trial in United States (drug, procedure, other)
Completed
- Adult Giant Cell Glioblastoma
- +3 more
- vismodegib
- +3 more
-
Los Angeles, California
- +8 more
Aug 15, 2017
Breast Cancer Trial in Pamplona (vismodegib, Paclitaxel, Epirubicin)
Unknown status
- Breast Cancer
- vismodegib
- +3 more
-
Pamplona, Navarra, SpainClínica Universidad de Navarra
Oct 23, 2017
Advanced Malignant Solid Tumor, Bladder Carcinoma, Breast Carcinoma Trial in Guam, Puerto Rico, United States (drug, procedure,
Recruiting
- Advanced Malignant Solid Neoplasm
- +49 more
- Adavosertib
- +36 more
-
Birmingham, Alabama
- +1429 more
Aug 17, 2022
Metastatic Colorectal Cancer Trial (Vismodegib 150 mg, Placebo to vismodegib, Bevacizumab)
Completed
- Metastatic Colorectal Cancer
- Vismodegib 150 mg
- +4 more
- (no location specified)
May 15, 2017
Ovarian Cancer Trial (Vismodegib 150 mg, Placebo to vismodegib)
Completed
- Ovarian Cancer
- Vismodegib 150 mg
- Placebo to vismodegib
- (no location specified)
May 15, 2017
Malignant Tumor Trial in Chicago (Pharmacological Study, Vismodegib)
Completed
- Malignant Neoplasm
- Pharmacological Study
- Vismodegib
-
Chicago, IllinoisUniversity of Chicago Comprehensive Cancer Center
Apr 11, 2017
Intracranial Meningioma, Recurrent Meningioma, NF2 Gene Mutation Trial in United States (Vismodegib, FAK Inhibitor GSK2256098,
Recruiting
- Intracranial Meningioma
- +2 more
- Vismodegib
- +3 more
-
Birmingham, Alabama
- +707 more
Sep 25, 2022
Basal Cell Carcinoma Trial in Saint Louis (vismodegib (150 mg PO daily))
Completed
- Basal Cell Carcinoma
- vismodegib (150 mg PO daily)
-
Saint Louis, MissouriSaint Louis University Department of Dermatology
May 1, 2019
Histologically Confirmed Medulloblastoma, Activation of the Sonic Hedgehog (SHH) Pathway Trial in Worldwide (vismodegib,
Terminated
- Histologically Confirmed Medulloblastoma
- Activation of the Sonic Hedgehog (SHH) Pathway
-
Marseille, Bouches Du Rhône, France
- +14 more
May 20, 2019