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GDC0449

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Clear Cell Chondrosarcoma, Dedifferentiated Chondrosarcoma, Locally Advanced Chondrosarcoma Trial in France (Laboratory

Active, not recruiting
  • Clear Cell Chondrosarcoma
  • +6 more
  • Laboratory Biomarker Analysis
  • +2 more
  • Bordeaux, France
  • +5 more
Sep 20, 2022

Chronic GVHD Trial in Ann Arbor, Salt Lake City (Laboratory Biomarker Analysis, Vismodegib)

Terminated
  • Chronic Graft Versus Host Disease
  • Ann Arbor, Michigan
  • +1 more
Jun 22, 2021

Basal Cell Nevus Syndrome, Gorlin Syndrome Trial in Oakland, New York (GDC-0449)

Completed
  • Basal Cell Nevus Syndrome
  • Gorlin Syndrome
  • Oakland, California
  • +1 more
Dec 16, 2020

Keratocystic Odontogenic Tumor Trial in New York (vismodegib)

Completed
  • Keratocystic Odontogenic Tumor
  • New York, New York
    NYU Bluestone Center For Cllinical Research
Feb 1, 2021

Basal Cell Nevus Syndrome, Gorlin's Syndrome Trial in Oakland, New York (Vismodegib, Aminolevulinic acid %20 topical solution)

Completed
  • Basal Cell Nevus Syndrome
  • Gorlin's Syndrome
  • Oakland, California
  • +2 more
Oct 8, 2020

Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma Trial in

Not yet recruiting
  • Anatomic Stage III Breast Cancer AJCC v8
  • +14 more
  • Biopsy
  • +25 more
  • Portland, Oregon
    OHSU Knight Cancer Institute
Jul 12, 2022

Metastatic Pancreatic Cancer Trial in Scottsdale, Baltimore, Philadelphia (Gemcitabine, nab-Paclitaxel, GDC-0449)

Completed
  • Metastatic Pancreatic Cancer
  • Gemcitabine, nab-Paclitaxel, GDC-0449
  • Scottsdale, Arizona
  • +2 more
Apr 2, 2019

Skin Basal Cell Carcinoma Trial in Palo Alto (Pembrolizumab, Vismodegib)

Completed
  • Skin Basal Cell Carcinoma
  • Palo Alto, California
    Stanford University School of Medicine
Mar 6, 2019

Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7, Stage IIB Prostate Cancer AJCC v7 Trial in United States (Goserelin

Terminated
  • Prostate Adenocarcinoma
  • +2 more
  • Goserelin Acetate
  • +3 more
  • Ann Arbor, Michigan
  • +4 more
Feb 6, 2019

Extensive Stage Small Cell Lung Carcinoma, Recurrent Small Cell Lung Carcinoma Trial in United States (drug, biological, other)

Completed
  • Extensive Stage Small Cell Lung Carcinoma
  • Recurrent Small Cell Lung Carcinoma
  • Scottsdale, Arizona
  • +300 more
Dec 10, 2020

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer Trial in

Completed
  • Acinar Cell Adenocarcinoma of the Pancreas
  • +4 more
  • Scottsdale, Arizona
  • +2 more
Apr 4, 2019

Solid Cancers Trial (GDC-0449)

Completed
  • Solid Cancers
  • (no location specified)
Jun 8, 2017

Recurrent Pancreatic Carcinoma, Stage IV Pancreatic Cancer Trial in Ann Arbor (Gemcitabine Hydrochloride, Laboratory Biomarker

Completed
  • Recurrent Pancreatic Carcinoma
  • Stage IV Pancreatic Cancer
  • Gemcitabine Hydrochloride
  • +2 more
  • Ann Arbor, Michigan
    University of Michigan Comprehensive Cancer Center
Aug 2, 2017

Healthy Trial (GDC-0449 oral capsules (non-labeled), GDC-0449 IV injection (labeled), CDC-0449 oral suspension (labeled))

Completed
  • Healthy
  • GDC-0449 oral capsules (non-labeled)
  • +2 more
  • (no location specified)
Jun 23, 2017

Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma Trial in United States (drug, procedure, other)

Completed
  • Adult Giant Cell Glioblastoma
  • +3 more
  • Los Angeles, California
  • +8 more
Aug 15, 2017

Breast Cancer Trial in Pamplona (vismodegib, Paclitaxel, Epirubicin)

Unknown status
  • Breast Cancer
  • Pamplona, Navarra, Spain
    Clínica Universidad de Navarra
Oct 23, 2017

Advanced Malignant Solid Tumor, Bladder Carcinoma, Breast Carcinoma Trial in Guam, Puerto Rico, United States (drug, procedure,

Recruiting
  • Advanced Malignant Solid Neoplasm
  • +49 more
  • Birmingham, Alabama
  • +1429 more
Aug 17, 2022

Metastatic Colorectal Cancer Trial (Vismodegib 150 mg, Placebo to vismodegib, Bevacizumab)

Completed
  • Metastatic Colorectal Cancer
  • Vismodegib 150 mg
  • +4 more
  • (no location specified)
May 15, 2017

Ovarian Cancer Trial (Vismodegib 150 mg, Placebo to vismodegib)

Completed
  • Ovarian Cancer
  • Vismodegib 150 mg
  • Placebo to vismodegib
  • (no location specified)
May 15, 2017

Malignant Tumor Trial in Chicago (Pharmacological Study, Vismodegib)

Completed
  • Malignant Neoplasm
  • Chicago, Illinois
    University of Chicago Comprehensive Cancer Center
Apr 11, 2017

Intracranial Meningioma, Recurrent Meningioma, NF2 Gene Mutation Trial in United States (Vismodegib, FAK Inhibitor GSK2256098,

Recruiting
  • Intracranial Meningioma
  • +2 more
  • Birmingham, Alabama
  • +707 more
Sep 25, 2022

Healthy Volunteer Trial (GDC-0449, moxifloxacin, )

Completed
  • Healthy Volunteer
  • (no location specified)
Feb 16, 2017

Basal Cell Carcinoma Trial in Saint Louis (vismodegib (150 mg PO daily))

Completed
  • Basal Cell Carcinoma
  • vismodegib (150 mg PO daily)
  • Saint Louis, Missouri
    Saint Louis University Department of Dermatology
May 1, 2019

Histologically Confirmed Medulloblastoma, Activation of the Sonic Hedgehog (SHH) Pathway Trial in Worldwide (vismodegib,

Terminated
  • Histologically Confirmed Medulloblastoma
  • Activation of the Sonic Hedgehog (SHH) Pathway
  • Marseille, Bouches Du Rhône, France
  • +14 more
May 20, 2019

Basal Cell Carcinoma Trial in Worldwide (vismodegib)

Completed
  • Basal Cell Carcinoma
  • Buenos Aires, Argentina
  • +180 more
Mar 4, 2019