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IONIS-ANGPTL3-Lrx

Showing 1 - 25 of 57
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED

Familial Chylomicronemia Syndrome, Lipoprotein Lipase Deficiency, Hyperlipoproteinemia Type 1 Trial in Montréal

Completed
Has Results
  • Familial Chylomicronemia Syndrome
  • +2 more
  • Montréal, Quebec, Canada
    Investigative Site
Dec 11, 2020

Hypertriglyceridemia, Familial Hypercholesterolemia Trial in Toronto (IONIS ANGPTL3-LRx, Placebo)

Completed
  • Hypertriglyceridemia
  • Familial Hypercholesterolemia
  • IONIS ANGPTL3-LRx
  • Placebo
  • Toronto, Ontario, Canada
    Clinical Site
Nov 17, 2020

Familial Partial Lipodystrophy Trial in Ann Arbor (AKCEA-ANGPTL3-LRx)

Completed
Has Results
  • Familial Partial Lipodystrophy
  • Ann Arbor, Michigan
    Clinical Site
Jan 27, 2021

NAFLD, Diabetes, Type 2, Hypertriglyceridemia Trial in Canada, United States (Placebo, ISIS 703802 40 mg, ISIS 703802 80 mg)

Completed
Has Results
  • NAFLD
  • +3 more
  • Placebo
  • +3 more
  • Chandler, Arizona
  • +41 more
Jan 28, 2021

Hereditary Angioedema Trial in Worldwide (Donidalorsen, Placebo)

Recruiting
  • Hereditary Angioedema
  • Scottsdale, Arizona
  • +48 more
Jan 25, 2023

Hypertension Trial in Canada, United States (IONIS-AGT-LRx, Placebo)

Active, not recruiting
  • Hypertension
  • Anniston, Alabama
  • +49 more
Aug 6, 2022

Acromegaly Trial in Worldwide (IONIS-GHR-LRx, Placebo)

Completed
Has Results
  • Acromegaly
  • Birmingham, Alabama
  • +32 more
Oct 21, 2022

Acromegaly Trial in Worldwide (IONIS GHR-LRx, SRL)

Completed
  • Acromegaly
  • Birmingham, Alabama
  • +21 more
Aug 4, 2022

Phlebotomy Dependent Polycythemia Vera Trial in Canada, United Kingdom, United States (IONIS-TMPRSS6-LRx)

Recruiting
  • Phlebotomy Dependent Polycythemia Vera
  • Orange, California
  • +4 more
Aug 1, 2022

Macular Degeneration, Geographic Atrophy Trial in Worldwide (IONIS-FB-LRx, Placebo)

Recruiting
  • Macular Degeneration
  • Geographic Atrophy
  • Phoenix, Arizona
  • +83 more
Aug 19, 2022

Hypertension Trial in United States (IONIS-AGT-LRx, Placebo)

Completed
Has Results
  • Hypertension
  • Placebo
  • ISIS 757456
  • Birmingham, Alabama
  • +8 more
Dec 21, 2022

Hereditary Angioedema Trial in Netherlands, United States (Donidalorsen)

Active, not recruiting
  • Hereditary Angioedema
  • Scottsdale, Arizona
  • +6 more
Aug 2, 2022

Beta Thalassemia Intermedia Trial in Worldwide (IONIS TMPRSS6-LRx)

Active, not recruiting
  • Beta Thalassemia Intermedia
  • Camperdown, New South Wales, Australia
  • +18 more
Sep 23, 2022

Homozygous Familial Hypercholesterolemia Trial in Québec (AKCEA-ANGPTL3-LRX)

Withdrawn
  • Homozygous Familial Hypercholesterolemia
  • Québec, Quebec, Canada
    Clinical Site
Nov 29, 2018

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy Trial in Indianapolis, Boston (Eplontersen)

Recruiting
  • Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
  • Indianapolis, Indiana
  • +19 more
Jan 31, 2023

Familial Chylomicronemia Syndrome Trial in Worldwide (Olezarsen)

Recruiting
  • Familial Chylomicronemia Syndrome
  • Huntington Beach, California
  • +4 more
Aug 4, 2022

Elevated Lipoprotein(a), Cardiovascular Disease Trial in Worldwide (ISIS 681257, Placebo)

Completed
Has Results
  • Elevated Lipoprotein(a)
  • Cardiovascular Disease
  • ISIS 681257
  • Placebo
  • Cottonwood, Arizona
  • +31 more
Oct 26, 2020

Chronic Heart Failure With Reduced Ejection Fraction Trial in Hungary, Poland, United States (IONIS-AGT-LRx, Placebo)

Active, not recruiting
  • Chronic Heart Failure With Reduced Ejection Fraction
  • Little Rock, Arkansas
  • +25 more
Jul 27, 2022

Hypertriglyceridemia, Cardiovascular Diseases Trial in Canada, United States (ISIS 678354, Placebo)

Completed
  • Hypertriglyceridemia
  • Cardiovascular Diseases
  • ISIS 678354
  • Placebo
  • Cottonwood, Arizona
  • +30 more
Nov 19, 2020

Familial Chylomicronemia Syndrome Trial in Canada, Sweden, United States (Olezarsen)

Recruiting
  • Familial Chylomicronemia Syndrome
  • Huntington Beach, California
  • +10 more
Aug 4, 2022

Healthy Participants Trial in Toronto (IONIS FXI-LRx, Placebo)

Completed
  • Healthy Participants
  • IONIS FXI-LRx
  • Placebo
  • Toronto, Ontario, Canada
    BioPharma Services Inc.
Jan 13, 2022

Hereditary Angioedema Trial in Netherlands, United States (IONIS-PKK-LRx, Placebo)

Completed
Has Results
  • Hereditary Angioedema
  • Scottsdale, Arizona
  • +7 more
Sep 15, 2022

Mild Hypertension Trial in United States (IONIS-AGT-LRx, Placebo)

Completed
  • Mild Hypertension
  • Tustin, California
  • +5 more
Nov 12, 2020

Familial Chylomicronemia Syndrome Trial in Worldwide (Olezarsen, Placebo)

Active, not recruiting
  • Familial Chylomicronemia Syndrome
  • Huntington Beach, California
  • +47 more
Aug 6, 2022

Hypertriglyceridemia, Atherosclerotic Cardiovascular Disease, Severe Hypertriglyceridemia Trial in Canada, United States

Active, not recruiting
  • Hypertriglyceridemia
  • +2 more
  • Lincoln, California
  • +23 more
Nov 23, 2022