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SCID

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The Experience of Screening for SCID

Recruiting
  • Severe Combined Immunodeficiency
  • SCID Screening
  • London, United Kingdom
    King's College London
Dec 6, 2022

Severe Combined Immune Deficiency (SCID) Trial run by the National Institute of Allergy and Infectious Diseases (NIAID)

Enrolling by invitation
  • Severe Combined Immune Deficiency (SCID)
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
Aug 24, 2022

Severe Combined Immunodeficiency, X Linked, Gene Therapy Trial in United Kingdom, United States (autologous CD34+ cell

Recruiting
  • Severe Combined Immunodeficiency, X Linked
  • Gene Therapy
  • autologous CD34+ cell transduced with G2SCID vector
  • Los Angeles, California
  • +4 more
Jul 19, 2022

Patients Previously Treated With Autologous ex Vivo Gene Therapy

Enrolling by invitation
  • Adenosine Deaminase Deficiency
  • Severe Combined Immunodeficiency (SCID)
  • autologous ex vivo gene therapy products based on the EFS LV encoding for the human adenosine deaminase (ADA) gene (EFS-ADA LV)
  • Los Angeles, California
  • +1 more
Mar 31, 2022

Severe Combined Immunodeficiency, X-Linked Trial in London (Lentiviral vector transduced CD34+ cells)

Recruiting
  • Severe Combined Immunodeficiency, X-Linked
  • Lentiviral vector transduced CD34+ cells
  • London, Greater London, United Kingdom
    Great Ormond Street Hospital for Children NHS Foundation Trust
Mar 15, 2022

Primary Immunodeficiency Diseases

Active, not recruiting
  • Wiskott- Aldrich Syndrome
  • ADA Deficient SCID
    • Bethesda, Maryland
      National Institutes of Health Clinical Center
    Jan 13, 2023

    Depressive; Episode, Major, Depression, Postpartum, Anxiety Disorders Trial (SCID 5)

    Not yet recruiting
    • Depressive; Episode, Major
    • +4 more
    • SCID 5
    • (no location specified)
    Jul 17, 2023

    X-linked Severe Combined Immunodeficiency Trial in Paris (Gene transfer)

    Completed
    • X-linked Severe Combined Immunodeficiency
    • Gene transfer
    • Paris, France
      Hopital Necker
    Sep 22, 2021

    SCID Trial in United States (Humanized anti-CD117 Monoclonal Antibody (JSP191))

    Recruiting
    • SCID
    • Humanized anti-CD117 Monoclonal Antibody (JSP191)
    • Los Angeles, California
    • +7 more
    Nov 16, 2021

    Severe Combined Immunodeficiency Trial in San Francisco (AProArt, CliniMACS® CD34 Reagent System cell sorter device, Busulfan)

    Recruiting
    • Severe Combined Immunodeficiency
    • San Francisco, California
      University of California, San Francisco (UCSF) Children's Hospit
    Feb 4, 2022

    Neonatal Screening of Severe Combined Immunodeficiencies

    Completed
    • Severe Combined Immunodeficiency
    • Neonatal Screening
      • Shanghai, Shanghai, China
        Children's Hospital of Fudan University
      Jan 3, 2022

      Severe Combined Immunodeficiency Due to ADA Deficiency Trial in London (Infusion of autologous cryopreserved EFS-ADA LV CD34+

      Active, not recruiting
      • Severe Combined Immunodeficiency Due to ADA Deficiency
      • Infusion of autologous cryopreserved EFS-ADA LV CD34+ cells (OTL-101)
      • +2 more
      • London, United Kingdom
        Great Ormond Street Hospital for Children NHS Foundation Trust
      Dec 17, 2021

      Severe Combined Immunodeficiency Trial in Memphis (drug, device, other)

      Recruiting
      • Severe Combined Immunodeficiency
      • Anti-thymocyte globulin (rabbit)
      • +5 more
      • Memphis, Tennessee
        St. Jude Children's Research Hospital
      Oct 6, 2021

      Through Imaging of Visceral Lymphoid Organs in SCID Who Have

      Completed
      • Severe Combined Immunodeficiency
        • Paris, France
          Hôpital Necker
        Jul 21, 2021

        Immunologic Deficiency Syndromes Trial in Milano (Strimvelis)

        Enrolling by invitation
        • Immunologic Deficiency Syndromes
        • Strimvelis
        • Milano, Lombardia, Italy
          Orchard Investigational Site
        Jun 23, 2021

        Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency Trial in Paris (ARTEGENE drug product)

        Not yet recruiting
        • Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency
        • ARTEGENE drug product
        • Paris, France
          Department of Pediatric Immunology, Hematology and Rheumatology
        Sep 26, 2022

        Pediatric Patients, Any Type of Severe Combined Immunodeficiency (SCID), Partial HLA Incompatible Allogeneic Hematopoietic Stem

        Recruiting
        • Pediatric Patients
        • +2 more
        • Human T Lymphoid Progenitor (HTLP) injection
        • Paris, Ile De France, France
          Unité d'Immunologie Hématologie Rhumatologie Pédiatrique (UIHR),
        Apr 13, 2021

        Severe Combined Immunodeficiency Due to RAG1 Deficiency Trial in Leiden (Gene therapy)

        Recruiting
        • Severe Combined Immunodeficiency Due to RAG1 Deficiency
        • Gene therapy
        • Leiden, Netherlands
          Leiden University Medical Center
        Dec 3, 2021

        Adenosine Deaminase Severe Combined Immune Deficiency Trial (A cryopreserved formulation of autologous mPB CD34+ hematopoietic

        Not yet recruiting
        • Adenosine Deaminase Severe Combined Immune Deficiency
        • A cryopreserved formulation of autologous mPB CD34+ hematopoietic stem and progenitor cells transduced ex vivo with the EFS-ADA lentiviral vector encoding the human ADA enzyme
        • (no location specified)
        Jun 20, 2022

        Participation in a Research Registry for Immune Disorders

        Recruiting
        • Primary Immunodeficiencies
        • +4 more
          • Bethesda, Maryland
            National Institutes of Health Clinical Center, 9000 Rockville Pi
          Apr 7, 2022

          Peripheral Immune System in Individuals With Schizophrenia

          Recruiting
          • Schizophrenia
          • +2 more
          • SCID (Standardized Clinical Interview for DSM-V)
          • +7 more
          • Stanford, California
            Stanford University School of Medicine
          Mar 15, 2022

          Severe Combined Immunodeficiency Trial in Los Angeles (ADA gene transfer)

          Completed
          Has Results
          • Severe Combined Immunodeficiency
          • ADA gene transfer
          • Los Angeles, California
            University of California, Los Angeles
          Apr 21, 2021

          Adenosine Deaminase Deficiency, Severe Combined Immunodeficiencies (SCID) Trial in London (genetic, other, drug)

          Completed
          Has Results
          • Adenosine Deaminase Deficiency
          • Severe Combined Immunodeficiencies (SCID)
          • Infusion of autologous EFS-ADA LV CD34+ cells
          • +3 more
          • London, United Kingdom
            Great Ormond Street Hospital for Children NHS Foundation Trust
          Aug 20, 2021

          Severe Combined Immunodeficiency (SCID), Immunodeficiency With Predominant T-cell Defect, Unspecified, Severe Chronic

          Enrolling by invitation
          • Severe Combined Immunodeficiency (SCID)
          • +8 more
          • CD3/CD19 negative allogeneic hematopoietic stem cells
          • Pittsburgh, Pennsylvania
            Children's Hospital of Pittsburgh of UPMC
          Dec 6, 2021

          Immunologic Deficiency Syndromes Trial in Jerusalem, Milano (Gene Therapy, Busulfan, PEG-ADA)

          Completed
          Has Results
          • Immunologic Deficiency Syndromes
          • Gene Therapy
          • +2 more
          • Jerusalem, Israel
          • +1 more
          Jul 15, 2020