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X-Linked Combined Immunodeficiency Diseases

Showing 1 - 25 of >10,000
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Severe Combined Immunodeficiency Disease, X-linked Trial in San Francisco, Memphis, Seattle (genetic, drug, device)

Recruiting
  • Severe Combined Immunodeficiency Disease, X-linked
  • CL20-i4-EF1α-hγc-OPT
  • +2 more
  • San Francisco, California
  • +2 more
Jan 9, 2023

X-linked Severe Combined Immunodeficiency (XSCID) Trial run by the National Institute of Allergy and Infectious Diseases (NIAID)

Suspended
  • X-linked Severe Combined Immunodeficiency (XSCID)
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
Aug 24, 2022

Severe Combined Immunodeficiency, X-Linked Trial in London (Lentiviral vector transduced CD34+ cells)

Recruiting
  • Severe Combined Immunodeficiency, X-Linked
  • Lentiviral vector transduced CD34+ cells
  • London, Greater London, United Kingdom
    Great Ormond Street Hospital for Children NHS Foundation Trust
Mar 15, 2022

X-linked Severe Combined Immunodeficiency Trial in Paris (Gene transfer)

Completed
  • X-linked Severe Combined Immunodeficiency
  • Gene transfer
  • Paris, France
    Hopital Necker
Sep 22, 2021

Severe Combined Immunodeficiency, X Linked, Gene Therapy Trial in United Kingdom, United States (autologous CD34+ cell

Recruiting
  • Severe Combined Immunodeficiency, X Linked
  • Gene Therapy
  • autologous CD34+ cell transduced with G2SCID vector
  • Los Angeles, California
  • +4 more
Jul 19, 2022

Gene Therapy Trial in Chongqing (Lentiviral Vector Gene Therapy)

Recruiting
  • Gene Therapy
  • Lentiviral Vector Gene Therapy
  • Chongqing, Chongqing, China
    Children's Hospital of Chongqing Medical University
Mar 26, 2020

Bone Marrow Failure Syndrome, Thalassemia, Sickle Cell Disease Trial in Gainesville (Thiotepa--single daily dose,

Recruiting
  • Bone Marrow Failure Syndrome
  • +15 more
  • Thiotepa--single daily dose
  • Thiotepa--escalated dose
  • Gainesville, Florida
    UF Health Shands Children's Hospital
Jul 8, 2021

Evaluation of Patients With Immune Function Abnormalities

Recruiting
  • Chronic Granulomatous Disease (CGD)
  • +3 more
    • Bethesda, Maryland
      National Institutes of Health Clinical Center, 9000 Rockville Pi
    Aug 24, 2022

    X-Linked Combined Immunodeficiency Diseases Trial run by the NIAID (CD34+ HSCs transduced with the lentivirus vector, VSV-G

    Unknown status
    • X-Linked Combined Immunodeficiency Diseases
    • CD34+ HSCs transduced with the lentivirus vector, VSV-G pseudotyped CL20-4i-EF1α-hγc-OPT
    • +2 more
    • Bethesda, Maryland
      Laboratory of Host Defenses (LHD), National Institute of Allergy
    Dec 3, 2019

    X-Linked Dystonia Parkinsonism Trial in Manila (transcranial magnetic resonance-guided focused ultrasound pallidothalamic

    Available
    • X-Linked Dystonia Parkinsonism
    • transcranial magnetic resonance-guided focused ultrasound pallidothalamic tractotomy
    • Manila, Philippines
      Philippine General Hospital
    Aug 21, 2022

    Immune Deficiency Disorders, Severe Combined Immunodeficiency, Chronic Granulomatous Disease Trial in Saint Louis (Transplant

    Recruiting
    • Immune Deficiency Disorders
    • +13 more
    • Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
    • Saint Louis, Missouri
      Washington University
    Apr 25, 2022

    Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and

    Recruiting
    • Granuloma
    • +4 more
      • Bethesda, Maryland
        National Institutes of Health Clinical Center
      Jan 25, 2023

      Immunodeficiency, Hematopoietic Stem Cell Transplantation Trial run by the National Cancer Institute (NCI) (drug, radiation,

      Recruiting
      • Immunodeficiency
      • Hematopoietic Stem Cell Transplantation
      • Post-Transplant Cyclophosphamide (PTCY)
      • +8 more
      • Bethesda, Maryland
        National Institutes of Health Clinical Center
      Aug 17, 2022

      X-linked Hypophosphatemia, Hypophosphatemic Rickets, Hypophosphatemic Rickets, X-Linked Dominant Trial in Boston (Calcitriol)

      Recruiting
      • X-linked Hypophosphatemia
      • +2 more
      • Boston, Massachusetts
        Massachusetts General Hospital
      Mar 16, 2022

      SCID, X Linked Trial in Beijing, Shenzhen (TYF-IL-2Rg gene-modified autologous stem cells)

      Unknown status
      • SCID, X Linked
      • TYF-IL-2Rg gene-modified autologous stem cells
      • Beijing, Beijing, China
      • +2 more
      Sep 18, 2019

      Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked Trial in Sacramento (Placebo Medication,

      Active, not recruiting
      • Fragile X Syndrome
      • +9 more
      • Sacramento, California
        UC Davis MIND Institute
      Feb 22, 2022

      X-Linked Myotubular Myopathy (XLMTM) Subjects

      Completed
      • X-linked Myotubular Myopathy
        • Los Angeles, California
        • +7 more
        Jul 27, 2022

        Exosome for Early Diagnosis of Bipolar Affective Disorder

        Not yet recruiting
        • Bipolar Affective Disorder
        • Major Depressive Disorder
          • Tianjin, China
            Tianjin Anding Hospital
          Jun 13, 2023

          COVID-19 Vaccine Responses in PIDD Subjects

          Recruiting
          • X-linked Agammaglobulinemia
          • +6 more
            • Saint Petersburg, Florida
            • +2 more
            Apr 7, 2022

            Development of Non-Invasive Prenatal Diagnosis for Single Gene

            Not yet recruiting
            • Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including
            • +14 more
            • Blood sample
            • Paris, France
              Hôpital Cochin, Maternité Port-Royal, service de Gynécologie obs
            Nov 24, 2023

            Multiple Myeloma Trial in Tianjin (anti-BCMA CAR-T, Selinexor-VRD)

            Recruiting
            • Multiple Myeloma
            • Tianjin, China
              Institute of Hematology and Blood Diseases Hospital Chinese Acad
            May 12, 2023

            Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X-Linked Trial in Edmonton, Montreal (Placebo

            Recruiting
            • Fragile X Syndrome
            • +9 more
            • Edmonton, Alberta, Canada
            • +1 more
            Sep 16, 2021

            Study of Smith-Lemli-Opitz Syndrome

            Completed
            • Smith-Lemli-Opitz Syndrome
            • Cholesterol Suspension
            • +2 more
            • Bethesda, Maryland
              National Institutes of Health Clinical Center
            Jan 25, 2023

            Human Immunodeficiency Virus I Infection Trial in Lyon (Blood collection.)

            Not yet recruiting
            • Human Immunodeficiency Virus I Infection
            • Blood collection.
            • Lyon, France
              Service des maladies infectieuses et tropicales Hôpital de la Cr
            Jan 21, 2022

            Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic Trial in Little Rock, Sacramento, Atlanta

            Recruiting
            • Muscular Dystrophies
            • +7 more
            • CAP-1002
            • Placebo
            • Little Rock, Arkansas
            • +9 more
            Jan 9, 2023