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LDE225

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STUDY
CONDITIONS
INTERVENTIONS
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Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma Trial in Rochester (Laboratory Biomarker Analysis, Lenalidomide,

Completed
Has Results
  • Recurrent Plasma Cell Myeloma
  • Refractory Plasma Cell Myeloma
  • Laboratory Biomarker Analysis
  • +2 more
  • Rochester, Minnesota
    Mayo Clinic
Dec 1, 2021

Basal Cell Carcinoma, Basal Cell Carcinoma of Skin, Site Unspecified, Skin Cancer Trial in North Sydney (drug, procedure, other)

Recruiting
  • Basal Cell Carcinoma
  • +3 more
  • North Sydney, New South Wales, Australia
    Melanoma Institute Australia
Jun 9, 2022

Advanced Solid Tumor Cancers, Medulloblastoma, Basal Cell Carcinoma Trial in Hong Kong, Japan, Taiwan (LDE225)

Completed
  • Advanced Solid Tumor Cancers
  • +2 more
  • LDE225
  • Hong Kong, Hong Kong
  • +3 more
Dec 16, 2020

Normal Hepatic Function, Impaired Hepatic Function Trial in Worldwide (LDE225)

Completed
  • Normal Hepatic Function
  • Impaired Hepatic Function
  • LDE225
  • Miami, Florida
  • +4 more
Dec 16, 2020

Advanced Solid Tumor Cancers, Medulloblastoma, Basal Cell Carcinoma Trial in Worldwide (LDE225)

Completed
  • Advanced Solid Tumor Cancers
  • +2 more
  • LDE225
  • Pittsburgh, Pennsylvania
  • +4 more
Dec 16, 2020

Pancreatic Cancer Trial in Spain, United Kingdom, United States (LDE225+gemcitabine)

Completed
  • Pancreatic Cancer
  • Boston, Massachusetts
  • +4 more
Dec 16, 2020

Philadelphia Chromosome Positive Chronic Myelogenous Leukemia Trial in Worldwide (Nilotinib + LDE225)

Completed
  • Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
  • Nilotinib + LDE225
  • Toronto, Ontario, Canada
  • +6 more
Dec 6, 2020

Pancreatic Cancer Trial in Boston (LDE225; Fluorouracil; Leucovorin; Oxaliplatin; Irinotecan)

Completed
  • Pancreatic Cancer
  • LDE225; Fluorouracil; Leucovorin; Oxaliplatin; Irinotecan
  • Boston, Massachusetts
  • +1 more
Jul 31, 2020

Advanced Solid Tumor Trial in United States (LDE225, Wafarin, Bupropion)

Completed
  • Advanced Solid Tumor
  • LDE225
  • +2 more
  • Duarte, California
  • +12 more
Dec 16, 2020

Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal

Recruiting
  • Clinical Stage III Cutaneous Melanoma AJCC v8
  • +38 more
  • Scottsdale, Arizona
  • +2 more
Aug 27, 2021

Esophageal Cancer Trial in Houston (Everolimus, LDE 225)

Completed
  • Esophageal Cancer
  • Houston, Texas
    University of Texas MD Anderson Cancer Center
Jun 10, 2020

Dose Escalation, Safety, Preliminary Efficacy Trial in Worldwide (LDE225, BKM120)

Completed
  • Dose Escalation
  • +11 more
  • Los Angeles, California
  • +22 more
Dec 16, 2020

Pancreatic Ductal Adenocarcinoma Trial in Baltimore (LDE225-600mg, Gemcitabine, nab-paclitaxel)

Terminated
Has Results
  • Pancreatic Ductal Adenocarcinoma
  • Baltimore, Maryland
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Jan 17, 2020

Solid Tumor, Ovarian Cancer Trial in Switzerland (LDE225, Paclitaxel)

Completed
  • Solid Tumor
  • Ovarian Cancer
  • Bellinzona, Switzerland
  • +3 more
Dec 5, 2019

Pancreatic Cancer Trial in Amsterdam (gemcitabine and nab paclitaxel)

Completed
  • Pancreatic Cancer
  • gemcitabine and nab paclitaxel
  • Amsterdam, Netherlands
    Academic Medical Center
Jan 7, 2020

Primary Myelofibrosis, Thrombocytosis, Essential Thrombocythemia Trial in Worldwide (LDE225, INC424)

Completed
Has Results
  • Primary Myelofibrosis
  • +9 more
  • Camperdown, New South Wales, Australia
  • +17 more
Apr 3, 2020

Prostate Cancer Trial in Hackensack (Docetaxel, Prednisone, LDE225)

Withdrawn
  • Prostate Cancer
  • Hackensack, New Jersey
    John Theurer Cancer @ HackensackUMC
Jun 17, 2019

Prostate Cancer Trial in Baltimore (LDE225)

Completed
Has Results
  • Prostate Cancer
  • LDE225
  • Baltimore, Maryland
    Johns Hopkins Hospital
Nov 13, 2018

Hepatocellular Carcinoma, Cirrhosis Trial in La Jolla (LDE225)

Completed
  • Hepatocellular Carcinoma
  • Cirrhosis
  • LDE225
  • La Jolla, California
    UCSD Moores Cancer Center
Mar 3, 2019

Advanced Breast Cancer Trial in Spain (LDE225, Docetaxel)

Completed
Has Results
  • Advanced Breast Cancer
  • A Coruña, Spain
  • +4 more
Dec 3, 2018

Carcinoma, Basal Cell, Recurrent Skin Cancer, Skin Tumors Trial in Stanford (Buparlisib, Sonidegib)

Terminated
Has Results
  • Carcinoma, Basal Cell
  • +3 more
  • Stanford, California
    Stanford University School of Medicine
Jan 10, 2019

Basal Cell Carcinoma Trial in Worldwide (LDE225)

Completed
Has Results
  • Basal Cell Carcinoma
  • LDE225
  • Fayetteville, Arkansas
  • +61 more
Aug 13, 2019

Cancer Target Therapy Efficacy

Active, not recruiting
  • Cancer
  • RNA sequencing
  • +5 more
  • Walnut, California
  • +6 more
Sep 13, 2021

Vismodegib (Erivedge®) in Advanced Basal Cell Carcinoma (BCC)

Completed
  • Basal Cell Carcinoma
  • Göteborg, Sweden
  • +3 more
Oct 8, 2020

GVHD Trial in Boston (LDE225)

Terminated
  • Graft Versus Host Disease
  • LDE225
  • Boston, Massachusetts
  • +2 more
Mar 15, 2018